"Vaccinating day-old chicks is essential for a healthy flock, and timing is everything. The ideal window is within the first 24 hours post-hatching, when their immune systems are primed to respond but before they’re exposed to pathogens. Here’s a typical vet-recommended schedule for day-old chicks:
- Marek’s Disease Vaccine: Administer at the hatchery or within 24-48 hours. It’s a subcutaneous injection (usually neck or thigh) to protect against this deadly, tumor-causing virus. Delaying past 72 hours reduces effectiveness as exposure risk rises.
- Newcastle Disease Vaccine: Given at 1 day old via drinking water, eye drop, or spray. This guards against a highly contagious respiratory disease. Vets may booster at 2-4 weeks depending on flock risk.
- Infectious Bronchitis Vaccine: Also applied at 1 day via spray or water, targeting another respiratory threat. A booster is often scheduled at 10-14 days.
Why Day 1Chicks hatch with maternal antibodies that wane fast—vaccines kickstart their own immunity at this vulnerable stage. Delaying even a few days can leave them defenseless against fast-spreading diseases. Work with your vet to tailor the plan—factors like local disease prevalence, flock size, and vaccine type (live vs. killed) affect timing and method. Precision in dosing and handling (e.g., avoiding stress or contamination) is key to success!"
Answers why" behind the timing.

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